Savona är en kommun och huvudort i provinsen Savona i regionen Ligurien i norra Italien. Savona gränsar till kommunerna Albissola Marina, Albisola Superiore, Altare, Cairo Montenotte, Quiliano och Vado Ligure.
S used to be one of the chief seats of the Italian iron industry, having iron-works and foundries, shipbuilding, railway workshops, engineering shops, and a brass foundry.
One of the most celebrated former inhabitants of S was the navigator Christopher Columbus, who farmed land in the area while chronicling his journeys. ‘Columbus’s house’, a cottage situated in the S hills, lay between vegetable crops and fruit trees. It is one of several residences in Liguria associated with Columbus.